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Targeted down-regulation of SRSF1 exerts anti-cancer activity in OSCC through impairing lysosomal function and autophagy

Oral squamous cell carcinoma (OSCC) is a common cancer of the head and neck. Despite ongoing efforts, there remains a dearth of targeted drugs capable of effectively inhibiting OSCC growth. As the earliest discovered proto-oncogene in the SRSF family, targeted inhibition of serine/arginine-rich spli...

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Detalles Bibliográficos
Autores principales: Qu, Yi, He, Ying, Wang, Yijuan, Han, Zhengxue, Qin, Lizheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663830/
https://www.ncbi.nlm.nih.gov/pubmed/38025785
http://dx.doi.org/10.1016/j.isci.2023.108330