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A highly specific antibody against the core fucose of the N-glycan in IgG identifies the pulmonary diseases and its regulation by CCL2

Glycan structure is often modulated in disease or predisease states, suggesting that such changes might serve as biomarkers. Here, we generated a monoclonal antibody (mAb) against the core fucose of the N-glycan in human IgG. Notably, this mAb can be used in Western blotting and ELISA. ELISA using t...

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Detalles Bibliográficos
Autores principales: Kanto, Noriko, Ohkawa, Yuki, Kitano, Masato, Maeda, Kento, Shiida, Masafumi, Ono, Tatsuya, Ota, Fumi, Kizuka, Yasuhiko, Kunimasa, Kei, Nishino, Kazumi, Mukai, Mikio, Seike, Masahiro, Azuma, Arata, Harada, Yoichiro, Fukuda, Tomohiko, Gu, Jianguo, Taniguchi, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663832/
https://www.ncbi.nlm.nih.gov/pubmed/37865317
http://dx.doi.org/10.1016/j.jbc.2023.105365