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Solid-to-liquid phase transition in the dissolution of cytosolic misfolded-protein aggregates

Accumulation of protein aggregates is a hallmark of cellular aging and degenerative disorders. This could result from either increased protein misfolding and aggregation or impaired dissolution of aggregates formed under stress, the latter of which is poorly understood. In this study, we employed qu...

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Detalles Bibliográficos
Autores principales: Tomaszewski, Alexis, Wang, Rebecca, Sandoval, Eduardo, Zhu, Jin, Liu, Jian, Li, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663836/
https://www.ncbi.nlm.nih.gov/pubmed/38025775
http://dx.doi.org/10.1016/j.isci.2023.108334