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Solid-to-liquid phase transition in the dissolution of cytosolic misfolded-protein aggregates
Accumulation of protein aggregates is a hallmark of cellular aging and degenerative disorders. This could result from either increased protein misfolding and aggregation or impaired dissolution of aggregates formed under stress, the latter of which is poorly understood. In this study, we employed qu...
Autores principales: | Tomaszewski, Alexis, Wang, Rebecca, Sandoval, Eduardo, Zhu, Jin, Liu, Jian, Li, Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663836/ https://www.ncbi.nlm.nih.gov/pubmed/38025775 http://dx.doi.org/10.1016/j.isci.2023.108334 |
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