Identification of the functional PD-L1 interface region responsible for PD-1 binding and initiation of PD-1 signaling

The PD-1/PD-L1 checkpoint pathway is important for regulating immune responses and can be targeted by immunomodulatory drugs to treat a variety of immune disorders. However, the precise protein–protein interactions required for the initiation of PD-1/PD-L1 signaling are currently unknown. Previously...

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Detalles Bibliográficos
Autores principales: Carter, Rachel, Alanazi, Fatimah, Sharp, Amanda, Roman, Jessica, Luchini, Alessandra, Liotta, Lance, Paige, Mikell, Brown, Anne M., Haymond, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
JBC Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663846/
https://www.ncbi.nlm.nih.gov/pubmed/37858677
http://dx.doi.org/10.1016/j.jbc.2023.105353

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663846/
https://www.ncbi.nlm.nih.gov/pubmed/37858677
http://dx.doi.org/10.1016/j.jbc.2023.105353

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