Metformin inhibits digestive proteases and impairs protein digestion in mice

Metformin is among the most prescribed medications worldwide and the first-line therapy for type 2 diabetes. However, gastrointestinal side effects are common and can be dose limiting. The total daily metformin dose frequently reaches several grams, and poor absorption results in high intestinal dru...

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Detalles Bibliográficos
Autores principales: Kelly, Caleb J., Verdegaal, Andrew A., Anderson, Brent W., Shaw, William L., Bencivenga-Barry, Natasha A., Folta-Stogniew, Ewa, Goodman, Andrew L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
JBC Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663847/
https://www.ncbi.nlm.nih.gov/pubmed/37863262
http://dx.doi.org/10.1016/j.jbc.2023.105363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663847/
https://www.ncbi.nlm.nih.gov/pubmed/37863262
http://dx.doi.org/10.1016/j.jbc.2023.105363

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