DOSE-L1000: unveiling the intricate landscape of compound-induced transcriptional changes

MOTIVATION: The LINCS L1000 project has collected gene expression profiles for thousands of compounds across a wide array of concentrations, cell lines, and time points. However, conventional analysis methods often fall short in capturing the rich information encapsulated within the L1000 transcript...

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Detalles Bibliográficos
Autores principales: Wang, Junmin, Novick, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663987/
https://www.ncbi.nlm.nih.gov/pubmed/37952162
http://dx.doi.org/10.1093/bioinformatics/btad683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663987/
https://www.ncbi.nlm.nih.gov/pubmed/37952162
http://dx.doi.org/10.1093/bioinformatics/btad683

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