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DOSE-L1000: unveiling the intricate landscape of compound-induced transcriptional changes
MOTIVATION: The LINCS L1000 project has collected gene expression profiles for thousands of compounds across a wide array of concentrations, cell lines, and time points. However, conventional analysis methods often fall short in capturing the rich information encapsulated within the L1000 transcript...
Autores principales: | Wang, Junmin, Novick, Steven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10663987/ https://www.ncbi.nlm.nih.gov/pubmed/37952162 http://dx.doi.org/10.1093/bioinformatics/btad683 |
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