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Design, synthesis and in silico evaluation of newer 1,4-dihydropyridine based amlodipine bio-isosteres as promising antihypertensive agents

Hypertension remains a major global health concern, prompting ongoing research into innovative therapeutic approaches. This research encompasses the strategic design, synthesis, and computational assessment of a novel series of 1,4-dihydropyridine based scaffolds with the objective of developing pro...

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Detalles Bibliográficos
Autores principales: Takkar, Priya, Singh, Bholey, Pani, Balaram, Kumar, Rakesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664005/
https://www.ncbi.nlm.nih.gov/pubmed/38020040
http://dx.doi.org/10.1039/d3ra06387a