In vitro anticancer effect of azithromycin targeting hypoxic lung cancer cells via the inhibition of mitophagy

Solid tumors are predisposed to hypoxia, which induces tumor progression, and causes resistance to treatment. Hypoxic tumor cells exploit auto- and mitophagy to facilitate metabolism and mitochondrial renewal. Azithromycin (AZM), a widely used macrolide, inhibits autophagy in cancer cells. The aim o...

Descripción completa

Detalles Bibliográficos
Autores principales: Toriyama, Kazutoshi, Okuma, Takashi, Abe, Shinji, Nakamura, Hiroyuki, Aoshiba, Kazutetsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664065/
https://www.ncbi.nlm.nih.gov/pubmed/38028184
http://dx.doi.org/10.3892/ol.2023.14146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664065/
https://www.ncbi.nlm.nih.gov/pubmed/38028184
http://dx.doi.org/10.3892/ol.2023.14146

Ejemplares similares