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STAT3 ameliorates truncated tau-induced cognitive deficits

Proteolytic cleavage of tau by asparagine endopeptidase (AEP) creates tau-N368 fragments, which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer’s disease patients. Nonetheless, the molecular mechanisms of truncated tau-induced cog...

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Detalles Bibliográficos
Autores principales: Zhang, Bingge, Wan, Huali, Maierwufu, Maimaitijiang, Liu, Qian, Li, Ting, He, Ye, Wang, Xin, Liu, Gongping, Hong, Xiaoyue, Feng, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664106/
https://www.ncbi.nlm.nih.gov/pubmed/37843229
http://dx.doi.org/10.4103/1673-5374.382253