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STAT3 ameliorates truncated tau-induced cognitive deficits
Proteolytic cleavage of tau by asparagine endopeptidase (AEP) creates tau-N368 fragments, which may drive the pathophysiology associated with synaptic dysfunction and memory deterioration in the brain of Alzheimer’s disease patients. Nonetheless, the molecular mechanisms of truncated tau-induced cog...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664106/ https://www.ncbi.nlm.nih.gov/pubmed/37843229 http://dx.doi.org/10.4103/1673-5374.382253 |