Cargando…
Dosage amplification dictates oncogenic regulation by the NKX2-1 lineage factor in lung adenocarcinoma
Amplified oncogene expression is a critical and widespread driver event in cancer, yet our understanding of how amplification-mediated elevated dosage mediates oncogenic regulation is limited. Here, we find that the most significant focal amplification event in lung adenocarcinoma (LUAD) targets a l...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664179/ https://www.ncbi.nlm.nih.gov/pubmed/37994369 http://dx.doi.org/10.1101/2023.10.26.563996 |