TH-302-loaded nanodrug reshapes the hypoxic tumour microenvironment and enhances PD-1 blockade efficacy in gastric cancer

BACKGROUND: Hypoxia, a common characteristic of the tumour microenvironment, is involved in tumour progression and immune evasion. Targeting the hypoxic microenvironment has been implicated as a promising antitumour therapeutic strategy. TH-302 can be selectively activated under hypoxic conditions....

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Detalles Bibliográficos
Autores principales: Wang, Zhixiong, Zhu, Menglin, Dong, Runyu, Cao, Danping, Li, Yanna, Chen, Zhiqiang, Cai, Juan, Zuo, Xueliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664313/
https://www.ncbi.nlm.nih.gov/pubmed/37993847
http://dx.doi.org/10.1186/s12951-023-02203-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664313/
https://www.ncbi.nlm.nih.gov/pubmed/37993847
http://dx.doi.org/10.1186/s12951-023-02203-8

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