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Detection of in vivo mutagenicity in rat liver samples using error-corrected sequencing techniques
BACKGROUND: Mutagenicity, the ability of chemical agents to cause mutations and potentially lead to cancer, is a critical aspect of substance safety assessment for protecting human health and the environment. Metabolic enzymes activate multiple mutagens in living organisms, thus in vivo animal model...
Autores principales: | Izawa, Kazuki, Tsuda, Masataka, Suzuki, Takayoshi, Honma, Masamitsu, Sugiyama, Kei-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664353/ https://www.ncbi.nlm.nih.gov/pubmed/37993952 http://dx.doi.org/10.1186/s41021-023-00288-z |
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