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The role of Nurr1-miR-30e-5p-NLRP3 axis in inflammation-mediated neurodegeneration: insights from mouse models and patients’ studies in Parkinson’s disease

Nuclear receptor related-1 (Nurr1), a ligand-activated transcription factor, is considered a potential susceptibility gene for Parkinson’s disease (PD), and has been demonstrated to possess protective effects against inflammation-induced neuronal damage. Despite the evidence showing decreased NURR1...

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Detalles Bibliográficos
Autores principales: Li, Tianbai, Tan, Xiang, Tian, Lulu, Jia, Congcong, Cheng, Cheng, Chen, Xi, Wei, Min, Wang, Yuanyuan, Hu, Yiying, Jia, Qiqi, Ni, Yang, Al-Nusaif, Murad, Li, Song, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664369/
https://www.ncbi.nlm.nih.gov/pubmed/37990334
http://dx.doi.org/10.1186/s12974-023-02956-x