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In Silico Identification of Natural Food Compounds as Potential Quorum-Sensing Inhibitors Targeting the LasR Receptor of Pseudomonas aeruginosa

Pseudomonas aeruginosa is a major cause of nosocomial infections and is often associated with biofilm-mediated antibiotic resistance. The LasR protein is a key component of the quorum system in P. aeruginosa, allowing it to regulate its biofilm-induced pathogenicity. When the bacterial population re...

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Detalles Bibliográficos
Autores principales: Magri, Meryam, Bouricha, El Mehdi, Hakmi, Mohammed, Jaoudi, Rachid EL, Belyamani, Lahcen, Ibrahimi, Azeddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664429/
https://www.ncbi.nlm.nih.gov/pubmed/38020496
http://dx.doi.org/10.1177/11779322231212755