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Captive ERVWE1 triggers impairment of 5-HT neuronal plasticity in the first-episode schizophrenia by post-transcriptional activation of HTR1B in ALKBH5-m6A dependent epigenetic mechanisms

BACKGROUND: Abnormalities in the 5-HT system and synaptic plasticity are hallmark features of schizophrenia. Previous studies suggest that the human endogenous retrovirus W family envelope (ERVWE1) is an influential risk factor for schizophrenia and inversely correlates with 5-HT4 receptor in schizo...

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Detalles Bibliográficos
Autores principales:	Wu, Xiulin, Liu, Lianzhong, Xue, Xing, Li, Xuhang, Zhao, Kexin, Zhang, Jiahang, Li, Wenshi, Yao, Wei, Ding, Shuang, Jia, Chen, Zhu, Fan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664518/ https://www.ncbi.nlm.nih.gov/pubmed/37990254 http://dx.doi.org/10.1186/s13578-023-01167-4

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