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TNF-α and IFN-γ prestimulation enhances the therapeutic efficacy of human amniotic epithelial stem cells in chemotherapy-induced ovarian dysfunction

BACKGROUND: Exposure to a harsh ovarian microenvironment induced by chemotherapeutic agents seriously affects the remodeling of ovarian function and follicular development, leading to premature ovarian failure or insufficiency (POF/POI). For decades, the effectiveness of stem cell therapies in POI a...

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Detalles Bibliográficos
Autores principales: Huang, Yating, Zhang, Qiuwan, Cao, Wenjiao, Zhang, Qinyu, Wang, Lulu, Lai, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664537/
https://www.ncbi.nlm.nih.gov/pubmed/37993924
http://dx.doi.org/10.1186/s41232-023-00309-y