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LIPH contributes to glycolytic phenotype in pancreatic ductal adenocarcinoma by activating LPA/LPAR axis and maintaining ALDOA stability

BACKGROUND: LIPH, a membrane-associated phosphatidic acid-selective phospholipase A1a, can produce LPA (Lysophosphatidic acid) from PA (Phosphatidic acid) on the outer leaflet of the plasma membrane. It is well known that LIPH dysfunction contributes to lipid metabolism disorder. Previous study show...

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Detalles Bibliográficos
Autores principales: Han, Lijie, Jiang, Yongsheng, Shi, Minmin, Gan, Lina, Wu, Zhichong, Xue, Meilin, Zhu, Youwei, Xiong, Cheng, Wang, Ting, Lin, Xiaozhu, Shen, Baiyong, Jiang, Lingxi, Chen, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664664/
https://www.ncbi.nlm.nih.gov/pubmed/37990271
http://dx.doi.org/10.1186/s12967-023-04702-6