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Single-cell transcriptomics reveals long noncoding RNAs associated with tumor biology and the microenvironment in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is highly heterogeneous and lethal. Long noncoding RNAs (lncRNAs) are an important class of genes regulating tumorigenesis and progression. Prior bulk transcriptomic studies in PDAC have revealed the dysregulation of lncRNAs but lack single-cell resolution to...

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Detalles Bibliográficos
Autores principales: Dang, Ha X, Saha, Debanjan, Jayasinghe, Reyka, Zhao, Sidi, Coonrod, Emily, Mudd, Jacqueline, Goedegebuure, S Peter, Fields, Ryan, Ding, Li, Maher, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664695/
https://www.ncbi.nlm.nih.gov/pubmed/38023733
http://dx.doi.org/10.1093/narcan/zcad055