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Sensing chemical-induced genotoxicity and oxidative stress via yeast-based reporter assays using NanoLuc luciferase

Mutagens and oxidative agents damage biomolecules, such as DNA; therefore, detecting genotoxic and oxidative chemicals is crucial for maintaining human health. To address this, we have developed several types of yeast-based reporter assays designed to detect DNA damage and oxidative stress. This stu...

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Detalles Bibliográficos
Autores principales: Shichinohe, Minami, Ohkawa, Shun, Hirose, Yuu, Eki, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10664910/
https://www.ncbi.nlm.nih.gov/pubmed/37992069
http://dx.doi.org/10.1371/journal.pone.0294571