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Structure of the native myosin filament in the relaxed cardiac sarcomere
The thick filament is a key component of sarcomeres, the basic units of striated muscle(1). Alterations in thick filament proteins are associated with familial hypertrophic cardiomyopathy and other heart and muscle diseases(2). Despite the central importance of the thick filament, its molecular orga...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665186/ https://www.ncbi.nlm.nih.gov/pubmed/37914933 http://dx.doi.org/10.1038/s41586-023-06690-5 |