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Structure of the native myosin filament in the relaxed cardiac sarcomere

The thick filament is a key component of sarcomeres, the basic units of striated muscle(1). Alterations in thick filament proteins are associated with familial hypertrophic cardiomyopathy and other heart and muscle diseases(2). Despite the central importance of the thick filament, its molecular orga...

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Detalles Bibliográficos
Autores principales: Tamborrini, Davide, Wang, Zhexin, Wagner, Thorsten, Tacke, Sebastian, Stabrin, Markus, Grange, Michael, Kho, Ay Lin, Rees, Martin, Bennett, Pauline, Gautel, Mathias, Raunser, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665186/
https://www.ncbi.nlm.nih.gov/pubmed/37914933
http://dx.doi.org/10.1038/s41586-023-06690-5