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Early-life stress perturbs the epigenetics of Cd36 concurrent with adult onset of NAFLD in mice

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is one of the most common liver diseases in the U.S. and worldwide. The roles of early postnatal life stress (EPLS) and the fatty acid translocase (CD36) on the pathogenesis of adult-onset NAFLD remain unknown. We hypothesized that EPLS, in the f...

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Detalles Bibliográficos
Autores principales: Fu, Qi, Frick, Jenna M., O’Neil, Maura F., Eller, Olivia C., Morris, E. Matthew, Thyfault, John P., Christianson, Julie A., Lane, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665193/
https://www.ncbi.nlm.nih.gov/pubmed/37479748
http://dx.doi.org/10.1038/s41390-023-02714-y