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Optimized, automated and cGMP-compliant synthesis of the HER2 targeting [(68)Ga]Ga-ABY-025 tracer

BACKGROUND: The Affibody molecule, ABY-025, has demonstrated utility to detect human epidermal growth factor receptor 2 (HER2) in vivo, either radiolabelled with indium-111 ((111)In) or gallium-68 ((68)Ga). Using the latter, (68)Ga, is preferred due to its use in positron emission tomography with su...

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Detalles Bibliográficos
Autores principales: Jussing, Emma, Ferrat, Mélodie, Moein, Mohammad M., Alfredéen, Henrik, Tegnebratt, Tetyana, Bratteby, Klas, Samén, Erik, Feldwisch, Joachim, Altena, Renske, Axelsson, Rimma, Tran, Thuy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665286/
https://www.ncbi.nlm.nih.gov/pubmed/37991639
http://dx.doi.org/10.1186/s41181-023-00226-y