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Common transthyretin-derived amyloid fibril structures in patients with hereditary ATTR amyloidosis

Systemic ATTR amyloidosis is an increasingly important protein misfolding disease that is provoked by the formation of amyloid fibrils from transthyretin protein. The pathological and clinical disease manifestations and the number of pathogenic mutational changes in transthyretin are highly diverse,...

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Detalles Bibliográficos
Autores principales: Steinebrei, Maximilian, Baur, Julian, Pradhan, Anaviggha, Kupfer, Niklas, Wiese, Sebastian, Hegenbart, Ute, Schönland, Stefan O., Schmidt, Matthias, Fändrich, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665346/
https://www.ncbi.nlm.nih.gov/pubmed/37993462
http://dx.doi.org/10.1038/s41467-023-43301-3