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Structure of the N-RNA/P interface indicates mode of L/P recruitment to the nucleocapsid of human metapneumovirus

Human metapneumovirus (HMPV) is a major cause of respiratory illness in young children. The HMPV polymerase (L) binds an obligate cofactor, the phosphoprotein (P). During replication and transcription, the L/P complex traverses the viral RNA genome, which is encapsidated within nucleoproteins (N). A...

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Detalles Bibliográficos
Autores principales: Whitehead, Jack D., Decool, Hortense, Leyrat, Cédric, Carrique, Loic, Fix, Jenna, Eléouët, Jean-François, Galloux, Marie, Renner, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665349/
https://www.ncbi.nlm.nih.gov/pubmed/37993464
http://dx.doi.org/10.1038/s41467-023-43434-5