Structure of the DDB1-AMBRA1 E3 ligase receptor complex linked to cell cycle regulation

AMBRA1 is a tumor suppressor protein that functions as a substrate receptor of the ubiquitin conjugation system with roles in autophagy and the cell cycle regulatory network. The intrinsic disorder of AMBRA1 has thus far precluded its structural determination. To solve this problem, we analyzed the...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Wang, Yang, Teng, Fei, Mai, Xinyi, Wang, Xi, Su, Ming-Yuan, Stjepanovic, Goran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665379/
https://www.ncbi.nlm.nih.gov/pubmed/37993427
http://dx.doi.org/10.1038/s41467-023-43174-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665379/
https://www.ncbi.nlm.nih.gov/pubmed/37993427
http://dx.doi.org/10.1038/s41467-023-43174-6

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