Cargando…

USP35 promotes HCC development by stabilizing ABHD17C and activating the PI3K/AKT signaling pathway

S-palmitoylation is a reversible protein lipidation that controls the subcellular localization and function of targeted proteins, including oncogenes such as N-RAS. The depalmitoylation enzyme family ABHD17s can remove the S-palmitoylation from N-RAS to facilitate cancer development. We previously s...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Linpei, Wang, Jiawei, Ma, Xiaoqiu, Ju, Guomin, Shi, Chunfeng, Wang, Wei, Wu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665393/
https://www.ncbi.nlm.nih.gov/pubmed/37993419
http://dx.doi.org/10.1038/s41420-023-01714-5