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USP35 promotes HCC development by stabilizing ABHD17C and activating the PI3K/AKT signaling pathway
S-palmitoylation is a reversible protein lipidation that controls the subcellular localization and function of targeted proteins, including oncogenes such as N-RAS. The depalmitoylation enzyme family ABHD17s can remove the S-palmitoylation from N-RAS to facilitate cancer development. We previously s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665393/ https://www.ncbi.nlm.nih.gov/pubmed/37993419 http://dx.doi.org/10.1038/s41420-023-01714-5 |