Distinct transcriptomic profiles in children prior to the appearance of type 1 diabetes-linked islet autoantibodies and following enterovirus infection

Although the genetic basis and pathogenesis of type 1 diabetes have been studied extensively, how host responses to environmental factors might contribute to autoantibody development remains largely unknown. Here, we use longitudinal blood transcriptome sequencing data to characterize host responses...

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Detalles Bibliográficos
Autores principales: Lin, Jake, Moradi, Elaheh, Salenius, Karoliina, Lehtipuro, Suvi, Häkkinen, Tomi, Laiho, Jutta E., Oikarinen, Sami, Randelin, Sofia, Parikh, Hemang M., Krischer, Jeffrey P., Toppari, Jorma, Lernmark, Åke, Petrosino, Joseph F., Ajami, Nadim J., She, Jin-Xiong, Hagopian, William A., Rewers, Marian J., Lloyd, Richard E., Rautajoki, Kirsi J., Hyöty, Heikki, Nykter, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665402/
https://www.ncbi.nlm.nih.gov/pubmed/37993433
http://dx.doi.org/10.1038/s41467-023-42763-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665402/
https://www.ncbi.nlm.nih.gov/pubmed/37993433
http://dx.doi.org/10.1038/s41467-023-42763-9

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