Cargando…

The heat shock protein LarA activates the Lon protease in response to proteotoxic stress

The Lon protease is a highly conserved protein degradation machine that has critical regulatory and protein quality control functions in cells from the three domains of life. Here, we report the discovery of a α-proteobacterial heat shock protein, LarA, that functions as a dedicated Lon regulator. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Omnus, Deike J., Fink, Matthias J., Kallazhi, Aswathy, Xandri Zaragoza, Maria, Leppert, Axel, Landreh, Michael, Jonas, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665427/
https://www.ncbi.nlm.nih.gov/pubmed/37993443
http://dx.doi.org/10.1038/s41467-023-43385-x