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The heat shock protein LarA activates the Lon protease in response to proteotoxic stress
The Lon protease is a highly conserved protein degradation machine that has critical regulatory and protein quality control functions in cells from the three domains of life. Here, we report the discovery of a α-proteobacterial heat shock protein, LarA, that functions as a dedicated Lon regulator. W...
Autores principales: | Omnus, Deike J., Fink, Matthias J., Kallazhi, Aswathy, Xandri Zaragoza, Maria, Leppert, Axel, Landreh, Michael, Jonas, Kristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665427/ https://www.ncbi.nlm.nih.gov/pubmed/37993443 http://dx.doi.org/10.1038/s41467-023-43385-x |
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