Megakaryocytes possess a STING pathway that is transferred to platelets to potentiate activation

Platelets display unexpected roles in immune and coagulation responses. Emerging evidence suggests that STING is implicated in hypercoagulation. STING is an adaptor protein downstream of the DNA sensor cyclic GMP-AMP synthase (cGAS) that is activated by cytosolic microbial and self-DNA during infect...

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Detalles Bibliográficos
Autores principales: El-Mortada, Firas, Landelouci, Karima, Bertrand-Perron, Samuel, Aubé, Félix-Antoine, Poirier, Amélie, Bidias, Amel, Jourdi, Georges, Welman, Mélanie, Gantier, Michael P, Hamilton, Justin R, Kile, Benjamin, Lordkipanidzé, Marie, Pépin, Geneviève
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665521/
https://www.ncbi.nlm.nih.gov/pubmed/37993259
http://dx.doi.org/10.26508/lsa.202302211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665521/
https://www.ncbi.nlm.nih.gov/pubmed/37993259
http://dx.doi.org/10.26508/lsa.202302211

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