The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy

Neurodegeneration and neuroinflammation are key processes of epileptogenesis in temporal lobe epilepsy (TLE). A considerable number (∼30%) of patients with epilepsy are resistant to currently available antiseizure drugs and thus there is a need to develop adjunct therapies to modify disease progress...

Descripción completa

Detalles Bibliográficos
Autores principales: Rao, Nikhil S., Putra, Marson, Meyer, Christina, Almanza, Aida, Thippeswamy, Thimmasettappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665569/
https://www.ncbi.nlm.nih.gov/pubmed/38025259
http://dx.doi.org/10.3389/fnmol.2023.1294514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665569/
https://www.ncbi.nlm.nih.gov/pubmed/38025259
http://dx.doi.org/10.3389/fnmol.2023.1294514

Ejemplares similares