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The effects of Src tyrosine kinase inhibitor, saracatinib, on the markers of epileptogenesis in a mixed-sex cohort of adult rats in the kainic acid model of epilepsy
Neurodegeneration and neuroinflammation are key processes of epileptogenesis in temporal lobe epilepsy (TLE). A considerable number (∼30%) of patients with epilepsy are resistant to currently available antiseizure drugs and thus there is a need to develop adjunct therapies to modify disease progress...
Autores principales: | Rao, Nikhil S., Putra, Marson, Meyer, Christina, Almanza, Aida, Thippeswamy, Thimmasettappa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665569/ https://www.ncbi.nlm.nih.gov/pubmed/38025259 http://dx.doi.org/10.3389/fnmol.2023.1294514 |
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