The discovery of hidden guanylate cyclases (GCs) in the Homo sapiens proteome

Recent discoveries have established functional guanylate cyclase (GC) catalytic centers with low activity within kinase domains in plants. These crypto GCs generate guanosine 3’,5’-cyclic monophosphate (cGMP) essential for both intramolecular and downstream signaling. Here, we have set out to search...

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Detalles Bibliográficos
Autores principales: Turek, Ilona, Freihat, Lubna, Vyas, Jignesh, Wheeler, Janet, Muleya, Victor, Manallack, David T., Gehring, Chris, Irving, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665587/
https://www.ncbi.nlm.nih.gov/pubmed/38022692
http://dx.doi.org/10.1016/j.csbj.2023.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665587/
https://www.ncbi.nlm.nih.gov/pubmed/38022692
http://dx.doi.org/10.1016/j.csbj.2023.11.005

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