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The discovery of hidden guanylate cyclases (GCs) in the Homo sapiens proteome
Recent discoveries have established functional guanylate cyclase (GC) catalytic centers with low activity within kinase domains in plants. These crypto GCs generate guanosine 3’,5’-cyclic monophosphate (cGMP) essential for both intramolecular and downstream signaling. Here, we have set out to search...
Autores principales: | Turek, Ilona, Freihat, Lubna, Vyas, Jignesh, Wheeler, Janet, Muleya, Victor, Manallack, David T., Gehring, Chris, Irving, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665587/ https://www.ncbi.nlm.nih.gov/pubmed/38022692 http://dx.doi.org/10.1016/j.csbj.2023.11.005 |
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