Bioactivity of dihydropyrimidinone derivatives as inhibitors of cyclooxygenase-2 (COX-2): an in silico approach

Cyclooxygenase-2 (COX-2) is an enzyme involved in inflammation. The overexpression of COX-2 causes chronic inflammation, which can be prevented by COX-2 inhibitors. Generally, COX-2 inhibitors possess a carboxyl group and an aromatic ring in their molecular structure. These moieties are involved in...

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Detalles Bibliográficos
Autores principales: Haq, Kautsar Ul, Sa'adah, Nur Lailatus, Siswanto, Imam, Suwito, Hery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665647/
https://www.ncbi.nlm.nih.gov/pubmed/38024961
http://dx.doi.org/10.1039/d3ra05942a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665647/
https://www.ncbi.nlm.nih.gov/pubmed/38024961
http://dx.doi.org/10.1039/d3ra05942a

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