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New oxindole carboxamides as inhibitors of DENV NS5 RdRp: Design, synthesis, docking and Biochemical characterization

Dengue is a mosquito-borne disease caused by the dengue virus belonging to family flaviviridae and has grown to be a major global public health issue. Despite decades of effort, the global comeback of dengue is evidence of the inadequacy of present management techniques. Due to the loss of healthy l...

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Detalles Bibliográficos
Autores principales: Koraboina, Chandra Prakash, Akshinthala, Parameswari, Katari, Naresh Kumar, Adarasandi, Ravi, Jonnalagadda, Sreekantha Babu, Gundla, Rambabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665688/
https://www.ncbi.nlm.nih.gov/pubmed/38027588
http://dx.doi.org/10.1016/j.heliyon.2023.e21510