Spatiotemporal regulation of GIPR signaling impacts glucose homeostasis as revealed in studies of a common GIPR variant

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) has a role in controlling postprandial metabolic tone. In humans, a GIP receptor (GIPR) variant (Q354, rs1800437) is associated with a lower body mass index (BMI) and increased risk for Type 2 Diabetes. To better understand the impacts of...

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Detalles Bibliográficos
Autores principales: Yammine, Lucie, Picatoste, Belén, Abdullah, Nazish, Leahey, Rosemary A., Johnson, Emma F., Gómez-Banoy, Nicolás, Rosselot, Carolina, Wen, Jennifer, Hossain, Tahmina, Goncalves, Marcus D., Lo, James C., Garcia-Ocaña, Adolfo, McGraw, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665708/
https://www.ncbi.nlm.nih.gov/pubmed/37925022
http://dx.doi.org/10.1016/j.molmet.2023.101831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665708/
https://www.ncbi.nlm.nih.gov/pubmed/37925022
http://dx.doi.org/10.1016/j.molmet.2023.101831

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