Guanylate-binding protein 1 modulates proteasomal machinery in ovarian cancer

Guanylate-binding protein 1 (GBP1) is known as an interferon-γ-induced GTPase. Here, we used genetically modified ovarian cancer (OC) cells to study the role of GBP1. The data generated show that GBP1 inhibition constrains the clonogenic potential of cancer cells. In vivo studies revealed that GBP1...

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Detalles Bibliográficos
Autores principales: Tailor, Dhanir, Garcia-Marques, Fernando Jose, Bermudez, Abel, Pitteri, Sharon J., Malhotra, Sanjay V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665831/
https://www.ncbi.nlm.nih.gov/pubmed/38026225
http://dx.doi.org/10.1016/j.isci.2023.108292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665831/
https://www.ncbi.nlm.nih.gov/pubmed/38026225
http://dx.doi.org/10.1016/j.isci.2023.108292

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