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IFNγ and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice

BACKGROUND & AIMS: The liver has a distinct capacity to induce immune tolerance to hepatic antigens. Although liver tolerance can be advantageous for preventing autoimmune and inflammatory diseases, it also can be detrimental by preventing immune surveillance of infected or malignant cells. Here...

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Detalles Bibliográficos
Autores principales: Krzikalla, Daria, Laschtowitz, Alena, Leypoldt, Lisa, Gottwick, Cornelia, Averhoff, Pia, Weidemann, Sören, Lohse, Ansgar W., Huber, Samuel, Schramm, Christoph, Schwinge, Dorothee, Herkel, Johannes, Carambia, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665921/
https://www.ncbi.nlm.nih.gov/pubmed/37734595
http://dx.doi.org/10.1016/j.jcmgh.2023.09.006