NCOA5 Haploinsufficiency in Myeloid-Lineage Cells Sufficiently Causes Nonalcoholic Steatohepatitis and Hepatocellular Carcinoma

BACKGROUND & AIMS: The nuclear receptor coactivator 5 (NCOA5) is a putative type 2 diabetes susceptibility gene. NCOA5 haploinsufficiency results in the spontaneous development of nonalcoholic fatty liver disease (NAFLD), insulin resistance, and hepatocellular carcinoma (HCC) in male mice; howev...

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Detalles Bibliográficos
Autores principales: Zhang, Yueqi, Luo, Yue, Liu, Xinhui, Kiupel, Matti, Li, Aimin, Wang, Hongbing, Mi, Qing-Sheng, Xiao, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665956/
https://www.ncbi.nlm.nih.gov/pubmed/37734594
http://dx.doi.org/10.1016/j.jcmgh.2023.09.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665956/
https://www.ncbi.nlm.nih.gov/pubmed/37734594
http://dx.doi.org/10.1016/j.jcmgh.2023.09.007

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