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Mice with FVB-derived sequence on chromosome 17 succumb to disseminated virus infection due to aberrant NK cell and T cell responses
Zoonotic arenavirus infections can result in viral hemorrhagic disease, characterized by platelet loss, petechia, and multi-organ injury. The mechanisms governing these outcomes are likely impacted by virus strain and infection dose, as well as an individual’s genetic background and immune constitut...
Autores principales: | Tibbs, Taylor N., Donoghue, Lauren J., Buzzelli, Ashlyn A., Misumi, Ichiro, DeMonia, Maggie, Ferris, Martin T., Kelada, Samir N.P., Whitmire, Jason K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10665959/ https://www.ncbi.nlm.nih.gov/pubmed/38026197 http://dx.doi.org/10.1016/j.isci.2023.108348 |
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