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Essential roles of the ANKRD31–REC114 interaction in meiotic recombination and mouse spermatogenesis

Meiotic DNA double-strand breaks (DSBs) initiate homologous recombination and are crucial for ensuring proper chromosome segregation. In mice, ANKRD31 recently emerged as a regulator of DSB timing, number, and location, with a particularly important role in targeting DSBs to the pseudoautosomal regi...

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Detalles Bibliográficos
Autores principales: Xu, Jiaqi, Li, Tao, Kim, Soonjoung, Boekhout, Michiel, Keeney, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666023/
https://www.ncbi.nlm.nih.gov/pubmed/37976262
http://dx.doi.org/10.1073/pnas.2310951120