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Simple and User-Friendly Methodology for Crystal Water Determination by Quantitative Proton NMR Spectroscopy in Deuterium Oxide

[Image: see text] In drug research and development, knowledge of the precise structure of an active ingredient is crucial. However, it is equally important to know the water content of the drug molecule, particularly the number of crystal waters present in its structure. Such knowledge ensures the a...

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Detalles Bibliográficos
Autores principales: Tynkkynen, Tuulia, Vassaki, Maria, Tiihonen, Tommi E., Lehto, Vesa-Pekka, Demadis, Konstantinos D., Turhanen, Petri A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666084/
https://www.ncbi.nlm.nih.gov/pubmed/37923567
http://dx.doi.org/10.1021/acs.analchem.3c03689