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A B cell–driven EAE mouse model reveals the impact of B cell–derived cytokines on CNS autoimmunity

In multiple sclerosis (MS), pathogenic T cell responses are known to be important drivers of autoimmune inflammation. However, increasing evidence suggests an additional role for B cells, which may contribute to pathogenesis via antigen presentation and production of proinflammatory cytokines. Howev...

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Detalles Bibliográficos
Autores principales: Thomann, Anna S., McQuade, Courtney A., Pinjušić, Katarina, Kolz, Anna, Schmitz, Rosa, Kitamura, Daisuke, Wekerle, Hartmut, Peters, Anneli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666104/
https://www.ncbi.nlm.nih.gov/pubmed/37956299
http://dx.doi.org/10.1073/pnas.2300733120