ReGeNNe: genetic pathway-based deep neural network using canonical correlation regularizer for disease prediction

MOTIVATION: Common human diseases result from the interplay of genes and their biologically associated pathways. Genetic pathway analyses provide more biological insight as compared to conventional gene-based analysis. In this article, we propose a framework combining genetic data into pathway struc...

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Detalles Bibliográficos
Autores principales: Sharma, Divya, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666205/
https://www.ncbi.nlm.nih.gov/pubmed/37963055
http://dx.doi.org/10.1093/bioinformatics/btad679

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666205/
https://www.ncbi.nlm.nih.gov/pubmed/37963055
http://dx.doi.org/10.1093/bioinformatics/btad679

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