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Comparative Atomistic Insights on Apo and ATP-I1171N/S/T in Nonsmall-Cell Lung Cancer

[Image: see text] Anaplastic lymphoma kinase (ALK) rearrangements occur in about 5% of nonsmall cell lung cancer (NSCLC) patients. Despite being first recognized as EML4-ALK, fusions with several additional genes have been identified, all of which cause constitutive activation of the ALK kinase and...

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Detalles Bibliográficos
Autores principales: Balasundaram, Ambritha, C Doss, George Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666221/
https://www.ncbi.nlm.nih.gov/pubmed/38027370
http://dx.doi.org/10.1021/acsomega.3c05785