Sculpting Secondary Structure of a Cyclic Peptide: Conformational Analysis of a Cyclic Hexapeptide Containing a Combination of l-Leu, d-Leu, and Aib Residues

[Image: see text] We have previously reported that cyclo(l-Leu-d-Leu-Aib-l-Leu-d-Leu-Aib) (2), a cyclic hexapeptide consisting of heterochiral l-Leu and d-Leu (l-Leu-d-Leu) residues with achiral 2-aminoisobutyric acid (Aib) residues, forms a figure-8 conformation. In this study, we newly designed cy...

Descripción completa

Detalles Bibliográficos
Autores principales: Ito, Takahito, Yokoo, Hidetomo, Kato, Takuma, Doi, Mitsunobu, Demizu, Yosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666233/
https://www.ncbi.nlm.nih.gov/pubmed/38027316
http://dx.doi.org/10.1021/acsomega.3c06397

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666233/
https://www.ncbi.nlm.nih.gov/pubmed/38027316
http://dx.doi.org/10.1021/acsomega.3c06397

Ejemplares similares