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Effect of Main and Side Chains on the Folding Mechanism of the Trp-Cage Miniprotein
[Image: see text] Proteins that do not fold into their functional native state have been linked to diseases. In this study, the influence of the main and side chains of individual amino acids on the folding of the tryptophan cage (Trp-cage), a designed 20-residue miniprotein, was analyzed. For this...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10666239/ https://www.ncbi.nlm.nih.gov/pubmed/38027385 http://dx.doi.org/10.1021/acsomega.3c05809 |